USMLE United States Medical Licensing Examination

USMLE stands for United States Medical Licensing Examination. This is a series of medical exams coming in a few stages that all new doctors need to pass (starting from their time in med school) to be able to practice medicine.
Step 1 of the USMLE (United States Medical Licensing Examination) is the first part of the United States Medical Licensing Examination. It is open to medical school student and graduates to assess their ability to apply important concepts fundamental to the practice of medicine. While American medical students usually take USMLE Step 1 at the end of the second year of medical school, all graduates of foreign medical schools must take this exam is they intend to practice medicine in the United States.
USMLE Step 2 is open to all medical students and graduates who have successfully passed the USMLE Step 1. The Step 2 exam assesses the candidates' medical knowledge, skills, and understanding of clinical science essential for patient treatment and care, health promotion and disease prevention.
Reference: http://www.usmle.org/step-1/#question-formats
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